Erica A. Golemis, PhD
Senior Member
Adjunct Associate Professor, University of Pennsylvania
Adjunct Professor, Drexel School of Medicine
Identifying and Targeting Signaling Hubs in Cancer
Recent Publications
2008
- Plotnikova, O.V., Golemis, E.A., and Pugacheva, E.N. Cell cycle-dependent ciliogenesis and cancer. Cancer Res., in press.
- Singh, M.K., Dadke, D., Nicolas, E., Serebriiskii, I.G., Apostolou, S., Canutescu, A., Egleston, B. L., and Golemis, E.A. A novel Cas-family member, HEPL, regulates FAK and cell spreading. Mol Biol Cell, in press, Epub Feb 6, 2008.
2007
- Izumchenko, E., Wolfson, M., Golemis, E.A., and Serebriiskii, I.G. Yeast hybrid approaches. Methods in Microbiol., 36:103-137, 2007.
- Khazak, V., Astsaturov, I., Serebriiskii, I.G., and Golemis, E.A. Selective Raf Inhibition in Cancer Therapy. Expert Opin .Ther. Targets. 11:1587-1609, 2007.
- Lee, H., Kim, D., Dan, H.D., Wu, E.L., Nicosia, S.V., Golemis, E.A., Liu, W., Coppola, D., Brem, S.S., Testa, J.R., and Cheng, J.Q. Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein. Mol Cell Biol, 27:2103-19, 2007.
- O’Neill, G.M., Seo, S., Serebriiskii, I.G., Lessin, S.R., and Golemis, E.A. A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. Cancer Res. 67:8975-8979, 2007.
- Pugacheva, E.N., Jablonski, S.A., Hartman, T.R., Henske, E.P, and Golemis, E.A. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell 129:1351-1363, 2007.
- Serebriiskii, I.G., Milech, N., and Golemis, E.A. A bacterial/yeast merged two-hybrid system: protocol for bacterial screening. Gene Function Analysis: Methods in Mol Biol. 408:291-315, 2007.
- Singh, M.K., Nicolas, E., Gherraby, W., Dadke, D., Lessin, S., and Golemis, E.A. HEI10 negatively regulates cell migration by inhibiting cyclin B/Cdk1 and other pro-motility proteins. Oncogene, 26:4825-32, 2007.
- Singh, M.K., Cowell, L., Seo, S., O’Neill, G.M., and Golemis, E.A. Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional coordinator of invasion, apoptosis and cell cycle. Cell Biochemistry and Biophysics, 48:54-72, 2007.
- Skobeleva, N., Menon, S., Weber, L., Golemis, E.A., and Khazak, V. In vitro and in vivo synergy of MCP compounds with MAPK pathway inhibitors and taxol. Mol. Cancer Ther. 6:898-906, 2007.
- Snell, W. J., and Golemis, E.A. A ciliary timer for S-phase entry. Nat. Rev. Mol Cell Biol. 8, 2007.